Regulation of endocytic pH by the Na+,K+-ATPase in living cells.
Acidification of endocytosed ligands destined for lysosomes is biphasic, with a rapid drop to pH 6, followed by a slow decrease to pH 5. Continuous measurements of transferrin acidification have confirmed that the pH minimum in early (presorting) endosomes is approximately pH 6. On the basis of meas...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.544 |
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