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Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development.

We have constructed an overexpression system in which the gene encoding the B subunit of cholera toxin (CTB) was placed under the control of the strong tacP promoter in a wide host range plasmid. Recombinant nontoxigenic classical and E1 Tor Vibrio cholerae strains of different serotypes harboring t...

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Autors principals: Sanchez, J, Holmgren, J
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC286494/
https://ncbi.nlm.nih.gov/pubmed/2492108
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