Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development.
We have constructed an overexpression system in which the gene encoding the B subunit of cholera toxin (CTB) was placed under the control of the strong tacP promoter in a wide host range plasmid. Recombinant nontoxigenic classical and E1 Tor Vibrio cholerae strains of different serotypes harboring t...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2492108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.481 |
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