α-Galactosidase A-Tat Fusion Enhances Storage Reduction in Hearts and Kidneys of Fabry Mice

The protein transduction domain from human immunodeficiency virus (HIV) Tat allows proteins to penetrate the cell membrane. Enhanced cellular uptake of therapeutic proteins could benefit a number of disorders. This is especially true for lysosomal storage disorders (LSDs) where enzyme replacement th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Higuchi, Koji, Yoshimitsu, Makoto, Fan, Xin, Guo, Xiaoxin, Rasaiah, Vanessa I, Yen, Jennifer, Tei, Chuwa, Takenaka, Toshihiro, Medin, Jeffrey A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: ScholarOne 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864812/
https://ncbi.nlm.nih.gov/pubmed/20454522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00163
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