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Progress in corticotropin-releasing factor-1 antagonist development

Corticotropin-releasing factor (CRF) receptor antagonists have been sought since the stress-secreted peptide was isolated in 1981. Although evidence suggests the limited efficacy of CRF(1) antagonists as antidepressants, CRF(1) antagonists might be novel pharmacotherapies for anxiety and addiction....

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Bibliografske podrobnosti
Main Authors: Zorrilla, Eric P., Koob, George F.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864802/
https://ncbi.nlm.nih.gov/pubmed/20206287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.02.011
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