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Progress in corticotropin-releasing factor-1 antagonist development
Corticotropin-releasing factor (CRF) receptor antagonists have been sought since the stress-secreted peptide was isolated in 1981. Although evidence suggests the limited efficacy of CRF(1) antagonists as antidepressants, CRF(1) antagonists might be novel pharmacotherapies for anxiety and addiction....
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864802/ https://ncbi.nlm.nih.gov/pubmed/20206287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.02.011 |
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