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Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses

In the course of infection or autoimmunity, particular transcription factors orchestrate the differentiation of T(H)1, T(H)2 or T(H)17 effector cells, the responses of which are limited by a distinct lineage of suppressive regulatory T cells (T(reg)). T(reg) cell differentiation and function are gui...

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Detalhes bibliográficos
Main Authors: Zheng, Ye, Chaudhry, Ashutosh, Kas, Arnold, deRoos, Paul, Kim, Jeong M., Chu, Tin-Tin, Corcoran, Lynn, Treuting, Piper, Klein, Ulf, Rudensky, Alexander Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864791/
https://ncbi.nlm.nih.gov/pubmed/19182775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07674
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