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CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells

BACKGROUND: Abnormal fatty acid composition (FA) in plasma and tissue lipids frequently occurs in homozygous and even in heterozygous carriers of cystic fibrosis transmembrane conductance regulator (CFTR) mutations. The mechanism(s) underlying these abnormalities remained, however, poorly understood...

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Autors principals: Mailhot, Geneviève, Rabasa-Lhoret, Rémi, Moreau, Alain, Berthiaume, Yves, Levy, Emile
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864762/
https://ncbi.nlm.nih.gov/pubmed/20463919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010446
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