Patterns of Antibody Binding to Aquaporin-4 Isoforms in Neuromyelitis Optica

BACKGROUND: Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG autoantibodies (Abs), a specific finding in NMO patients, target the water channel protein aquaporin-4 (AQP4), which is expres...

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Main Authors: Mader, Simone, Lutterotti, Andreas, Di Pauli, Franziska, Kuenz, Bettina, Schanda, Kathrin, Aboul-Enein, Fahmy, Khalil, Michael, Storch, Maria K., Jarius, Sven, Kristoferitsch, Wolfgang, Berger, Thomas, Reindl, Markus
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864757/
https://ncbi.nlm.nih.gov/pubmed/20463974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010455
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