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Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC-205/CD205 positive mouse dendritic cells
There is a need for a more efficient vaccine against the bacterium Y. pestis, the agent of pneumonic plague. The F1-LcrV subunit vaccine in alhydrogel is known to induce humoral immunity. In this study, we utilized dendritic cells to investigate cellular immunity. We genetically engineered the LcrV...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864640/ https://ncbi.nlm.nih.gov/pubmed/18081041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737799 |
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