Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC-205/CD205 positive mouse dendritic cells

There is a need for a more efficient vaccine against the bacterium Y. pestis, the agent of pneumonic plague. The F1-LcrV subunit vaccine in alhydrogel is known to induce humoral immunity. In this study, we utilized dendritic cells to investigate cellular immunity. We genetically engineered the LcrV...

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Detaylı Bibliyografya
Asıl Yazarlar: Do, Yoonkyung, Park, Chae Gyu, Kang, Young-Sun, Park, Sung Ho, Lynch, Rebecca M., Lee, Haekyung, Powell, Bradford S., Steinman, Ralph M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864640/
https://ncbi.nlm.nih.gov/pubmed/18081041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737799
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