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Supraspinally-administered agmatine attenuates the development of oral fentanyl self-administration
The decarboxylation product of arginine, agmatine, has effectively reduced or prevented opioid-induced tolerance and dependence when given either systemically (intraperitoneally or subcutaneously) or centrally (intrathecally or intracerebroventricularly). Systemically administered agmatine also redu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864631/ https://ncbi.nlm.nih.gov/pubmed/18495108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.04.007 |
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