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Detection and correction of false segmental duplications caused by genome mis-assembly

Diploid genomes with divergent chromosomes present special problems for assembly software as two copies of especially polymorphic regions may be mistakenly constructed, creating the appearance of a recent segmental duplication. We developed a method for identifying such false duplications and applie...

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Detalles Bibliográficos
Main Authors: Kelley, David R, Salzberg, Steven L
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864568/
https://ncbi.nlm.nih.gov/pubmed/20219098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-3-r28
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