Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence

BACKGROUND: Previous studies have suggested that recent segmental duplications, which are often involved in chromosome rearrangements underlying genomic disease, account for some 5% of the human genome. We have developed rapid computational heuristics based on BLAST analysis to detect segmental dupl...

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Detalhes bibliográficos
Main Authors: Cheung, Joseph, Estivill, Xavier, Khaja, Razi, MacDonald, Jeffrey R, Lau, Ken, Tsui, Lap-Chee, Scherer, Stephen W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154576/
https://ncbi.nlm.nih.gov/pubmed/12702206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2003-4-4-r25
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