Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop

A significant fraction of CD1d-restricted T cells express an invariant T cell receptor (TCR) α-chain. These highly conserved ‘iNKT’ populations are important regulators of a wide spectrum of immune responses. The ability to directly identify and manipulate iNKT is essential to understanding their fu...

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Main Authors: Exley, Mark A., Hou, Runhua, Shaulov, Angela, Dellabona, Paolo, Casorati, Giulia, Akbari, Omid, Akman, H. Orhan, Greenfield, Edward A., Gumperz, Jenny E., Boyson, Jonathan E., Balk, Steven P., Wilson, S. Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864538/
https://ncbi.nlm.nih.gov/pubmed/18493987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737389
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