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LAMBDA AND ALPHA INTERFERONS INHIBIT HEPATITIS B VIRUS REPLICATION THROUGH A COMMON MOLECULAR MECHANISM BUT WITH DIFFERENT IN VIVO ACTIVITIES
The type III interferons (IFN-λ1, 2, 3) induce an antiviral response similar to IFN-α/β, but mediate their activity through a unique receptor. We found that like IFN-α/β, IFN-λ prevents the assembly of HBV capsids, demonstrating convergence of the two signaling pathways through a single antiviral me...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864496/ https://ncbi.nlm.nih.gov/pubmed/20303135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.02.022 |
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