Interleukin-29 Functions Cooperatively with Interferon to Induce Antiviral Gene Expression and Inhibit Hepatitis C Virus Replication

The interferon (IFN)-related cytokine interleukin (IL)-29 (also known as IFN-λ1) inhibits virus replication by inducing a cellular antiviral response similar to that activated by IFN-α/β. However, because it binds to a unique receptor, this cytokine may function cooperatively with IFN-α/β or IFN-γ d...

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Main Authors: Pagliaccetti, Nicole E., Eduardo, Roger, Kleinstein, Steven H., Mu, Xinmeng Jasmine, Bandi, Prasanthi, Robek, Michael D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662072/
https://ncbi.nlm.nih.gov/pubmed/18757365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804296200
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