Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats.

Adjuvant arthritis in rats is a T-cell dependent "autoimmune" disease with close similarities to several forms of human arthritis. Injection of mycobacterial adjuvant leads to T-cell activation and proliferation, processes in which the de novo expression of the interleukin 2 (IL-2) recepto...

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Détails bibliographiques
Auteurs principaux: Case, J P, Lorberboum-Galski, H, Lafyatis, R, FitzGerald, D, Wilder, R L, Pastan, I
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC286449/
https://ncbi.nlm.nih.gov/pubmed/2492102
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