Silibinin Suppresses Growth of Human Colorectal Carcinoma SW480 Cells in Culture and Xenograft through Down-regulation of β-Catenin-Dependent Signaling

Mutations in APC/β-catenin resulting in an aberrant activation of Wnt/β-catenin pathway are common in colorectal cancer (CRC), suggesting that targeting the β-catenin pathway with chemopreventive/anticancer agents could be a potential translational approach to control CRC. Using human CRC cell lines...

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Hlavní autoři: Kaur, Manjinder, Velmurugan, Balaiya, Tyagi, Alpna, Agarwal, Chapla, Singh, Rana P, Agarwal, Rajesh
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864479/
https://ncbi.nlm.nih.gov/pubmed/20454513
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