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Silibinin Suppresses Spontaneous Tumorigenesis in APC(min/+) Mouse Model by Modulating Beta-Catenin Pathway
PURPOSE: Here we assessed whether silibinin, a nontoxic chemopreventive agent, inhibits spontaneous intestinal tumorigenesis in APC(m)(in/+) mouse model, a genetically predisposed animal model of human familial adenomatous polyposis (FAP). MATERIALS AND METHODS: Six-week old APC(min/+) mice were div...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809789/ https://ncbi.nlm.nih.gov/pubmed/19779968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9968-1 |
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