Three-dimensionally Specific Inhibition of DNA Repair-Related Genes by Activated KRAS in Colon Crypt Model

Growth and differentiation of colonic epithelium are regulated in the three-dimensional (3D) physiological architecture, colonic crypt, and deregulation of 3D interactions is involved in tumorigenesis. Cell-based 3D culture systems provide a suitable approach bridging the gap between two-dimensional...

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Bibliografski detalji
Glavni autori: Tsunoda, Toshiyuki, Takashima, Yasuo, Fujimoto, Takahiro, Koyanagi, Midori, Yoshida, Yasuhiro, Doi, Keiko, Tanaka, Yoko, Kuroki, Masahide, Sasazuki, Takehiko, Shirasawa, Senji
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864477/
https://ncbi.nlm.nih.gov/pubmed/20454511
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