Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes

Background. Estrogen plays a major role in endometrial carcinogenesis, suggesting that common variants of genes in the sex hormone metabolic pathway may be related to endometrial cancer risk. In support of this view, variants in CYP19A1 [cytochrome P450 (CYP), family 19, subfamily A, polypeptide 1]...

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Autors principals: Yang, Hannah P., Gonzalez Bosquet, Jesus, Li, Qizhai, Platz, Elizabeth A., Brinton, Louise A., Sherman, Mark E., Lacey, James V., Gaudet, Mia M., Burdette, Laurie A., Figueroa, Jonine D., Ciampa, Julia G., Lissowska, Jolanta, Peplonska, Beata, Chanock, Stephen J., Garcia-Closas, Montserrat
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Molecular Epidemiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864407/
https://ncbi.nlm.nih.gov/pubmed/20053928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp328
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