Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes

Background. Estrogen plays a major role in endometrial carcinogenesis, suggesting that common variants of genes in the sex hormone metabolic pathway may be related to endometrial cancer risk. In support of this view, variants in CYP19A1 [cytochrome P450 (CYP), family 19, subfamily A, polypeptide 1]...

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Detalhes bibliográficos
Main Authors: Yang, Hannah P., Gonzalez Bosquet, Jesus, Li, Qizhai, Platz, Elizabeth A., Brinton, Louise A., Sherman, Mark E., Lacey, James V., Gaudet, Mia M., Burdette, Laurie A., Figueroa, Jonine D., Ciampa, Julia G., Lissowska, Jolanta, Peplonska, Beata, Chanock, Stephen J., Garcia-Closas, Montserrat
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864407/
https://ncbi.nlm.nih.gov/pubmed/20053928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp328
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