A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease

BACKGROUND: Cells respond to stress stimuli through a number of response pathways, of which one of the most important and well characterized is the unfolded protein response. Despite a large body of work which suggests that stress in erythroblasts may play a pivotal role in the pathogenesis of β-tha...

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Autores principales: Lithanatudom, Pathrapol, Leecharoenkiat, Amporn, Wannatung, Tirawat, Svasti, Saovaros, Fucharoen, Suthat, Smith, Duncan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864376/
https://ncbi.nlm.nih.gov/pubmed/20015891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.015701
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