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Macromolecular organization of human centromeric regions reveals high-frequency, polymorphic macro DNA repeats.

To analyze the macromolecular organization of human centromeric regions, we used alpha-satellite, or alphoid, repetitive DNA sequences specific to the centromeres of human chromosomes 6 (D6Z1), X (XC), and Y (YC-2) and the technique of pulsed-field gel electrophoresis. Genomic DNA from 24 normal, un...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Jabs, E W, Goble, C A, Cutting, G R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911568/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.202
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