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Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA

Despite critical roles in chromosome segregation and disease, the repetitive structure and vast size of centromeres and their surrounding heterochromatic regions impede studies of genomic variation. Here we report the identification of large-scale haplotypes (cenhaps) in humans that span the centrom...

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Pubblicato in:eLife
Autori principali: Langley, Sasha A, Miga, Karen H, Karpen, Gary H, Langley, Charles H
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592686/
https://ncbi.nlm.nih.gov/pubmed/31237235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42989
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