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Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA

Despite critical roles in chromosome segregation and disease, the repetitive structure and vast size of centromeres and their surrounding heterochromatic regions impede studies of genomic variation. Here we report the identification of large-scale haplotypes (cenhaps) in humans that span the centrom...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Langley, Sasha A, Miga, Karen H, Karpen, Gary H, Langley, Charles H
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592686/
https://ncbi.nlm.nih.gov/pubmed/31237235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42989
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