Taurine deficiency damages photoreceptors and retinal ganglion cells in vigabatrin-treated neonatal rats

The anti-epileptic drug Vigabatrin induces an irreversible constriction of the visual field, but is still widely used to treat infantile spasms and some forms of epilepsy. We recently reported that vigabatrin-induced cone damage is due to a taurine deficiency. However, optic atrophy and thus retinal...

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Main Authors: Jammoul, Firas, Dégardin, Julie, Pain, Dorothée, Gondouin, Pauline, Simonutti, Manuel, Dubus, Elisabeth, Caplette, Romain, Fouquet, Stéphane, Craft, Cheryl M., Sahel, José A., Picaud, Serge
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864319/
https://ncbi.nlm.nih.gov/pubmed/20132888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.01.008
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