Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity

OBJECTIVE: Although vigabatrin irreversibly constricts the visual field, it remains a potent therapy for infantile spasms and a third-line drug for refractory epilepsies. In albino animals, this drug induces a reduction in retinal cell function, retinal disorganisation and cone photoreceptor damage....

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Autors principals: Jammoul, Firas, Wang, Qingping, Nabbout, Rimas, Coriat, Caroline, Duboc, Agnès, Simonutti, Manuel, Dubus, Elisabeth, Craft, Cheryl M., Ye, Wen, Collins, Stephen D., Dulac, Olivier, Chiron, Catherine, Sahel, José A., Picaud, Serge
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665303/
https://ncbi.nlm.nih.gov/pubmed/19194884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21526
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