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Diverse Effects on Mitochondrial and Nuclear Functions Elicited by Drugs and Genetic Knockdowns in Bloodstream Stage Trypanosoma brucei

BACKGROUND: The options for treating the fatal disease human African trypanosomiasis are limited to a few drugs that are toxic or facing increasing resistance. New drugs that kill the causative agents, subspecies of Trypanosoma brucei, are therefore urgently needed. Little is known about the cellula...

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Autori principali: Worthen, Christal, Jensen, Bryan C., Parsons, Marilyn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864271/
https://ncbi.nlm.nih.gov/pubmed/20454560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000678
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