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Major role for mRNA stability in shaping the kinetics of gene induction

BACKGROUND: mRNA levels in cells are determined by the relative rates of RNA production and degradation. Yet, to date, most analyses of gene expression profiles were focused on mechanisms which regulate transcription, while the role of mRNA stability in modulating transcriptional networks was to a l...

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Detalhes bibliográficos
Main Authors: Elkon, Ran, Zlotorynski, Eitan, Zeller, Karen I, Agami, Reuven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864252/
https://ncbi.nlm.nih.gov/pubmed/20409322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-259
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