Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

BACKGROUND: Tyrosine kinase 2 (Tyk2), a central component of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling, has major effects on innate immunity and inflammation. Mice lacking Tyk2 are resistant to endotoxin shock induced by lipopolysaccharide (LPS), and Tyk2 def...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vogl, Claus, Flatt, Thomas, Fuhrmann, Bernd, Hofmann, Elisabeth, Wallner, Barbara, Stiefvater, Rita, Kovarik, Pavel, Strobl, Birgit, Müller, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864243/
https://ncbi.nlm.nih.gov/pubmed/20338026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-199
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados