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Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes.
Seven morphologically nontransformed (flat) revertants with reduced tumorigenicity in vivo have been isolated from populations of Kirsten sarcoma virus-transformed NIH 3T3 cells transfected with a cDNA expression library of normal human fibroblasts. Each revertant harbors 1-10 recombinant plasmids p...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1989
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2463620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.162 |
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