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Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent

BACKGROUND: Antisense reagents can serve as efficient and versatile tools for studying gene function by inhibiting nucleic acids in vivo. Antisense reagents have particular utility for the experimental manipulation of the activity of microRNAs (miRNAs), which are involved in the regulation of divers...

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Bibliographic Details
Main Authors: Zheng, Genhua, Ambros, Victor, Li, Wen-hong
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864223/
https://ncbi.nlm.nih.gov/pubmed/20359322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-1-9
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