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A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans

Animal development is remarkably robust; cell fates are specified with spatial and temporal precision despite physiological and environmental contingencies. Favorable conditions cause Caenorhabditis elegans to develop rapidly through four larval stages (L1–L4) to the reproductive adult. In unfavorab...

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Bibliografiske detaljer
Main Authors: Hammell, Christopher M., Karp, Xantha, Ambros, Victor
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774035/
https://ncbi.nlm.nih.gov/pubmed/19828440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908131106
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