RNA polymerase II is capable of pausing and prematurely terminating transcription at a precise location in vivo and in vitro.
By using the minute virus of mice, we have shown that in vivo and in vitro RNA polymerase II pauses or prematurely terminates transcription at a specific location 142-147 nucleotides downstream from the P4 promoter. The attenuated RNA was found and mapped in vivo in A9 cell late after infection in b...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.12 |
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