Transcription pausing regulates mouse embryonic stem cell differentiation

The pluripotency of embryonic stem cells (ESCs) relies on appropriate responsiveness to developmental cues. Promoter-proximal pausing of RNA polymerase II (Pol II) has been suggested to play a role in keeping genes poised for future activation. To identify the role of Pol II pausing in regulating ES...

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Bibliografiske detaljer

Principais autores:	Melodi Tastemel, Aishwarya A. Gogate, Venkat S. Malladi, Kim Nguyen, Courtney Mitchell, Laura A. Banaszynski, Xiaoying Bai
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2017-12-01
Serier:	Stem Cell Research
Fag:	Transcription pausing Mouse embryonic stem cell Global run-on sequencing (GRO-seq)
Online adgang:	http://www.sciencedirect.com/science/article/pii/S1873506117302428
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