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Human Papillomavirus Type 16 E6/E7 Upregulation of Nucleophosmin Is Important for Proliferation and Inhibition of Differentiation

The E6 and E7 oncoproteins of high-risk human papillomaviruses (HPVs) are together sufficient to cause cellular transformation. Nucleophosmin (NPM) was identified as a protein with increased levels in two-dimensional (2-D) gel analysis of human foreskin keratinocytes (HFKs) expressing E7 following m...

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Détails bibliographiques
Auteurs principaux: McCloskey, Rachel, Menges, Craig, Friedman, Alan, Patel, Daksha, McCance, Dennis J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863842/
https://ncbi.nlm.nih.gov/pubmed/20237089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01965-09
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