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Binding Site on the Transferrin Receptor for the Parvovirus Capsid and Effects of Altered Affinity on Cell Uptake and Infection

Canine parvovirus (CPV) and its relative feline panleukopenia virus (FPV) bind the transferrin receptor type 1 (TfR) to infect their host cells but show differences in the interactions with the feline and canine TfRs that determine viral host range and tissue tropism. We changed apical and protease-...

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Autores principales: Goodman, Laura B., Lyi, Sangbom M., Johnson, Natalie C., Cifuente, Javier O., Hafenstein, Susan L., Parrish, Colin R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863798/
https://ncbi.nlm.nih.gov/pubmed/20200243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02623-09
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