Binding Site on the Transferrin Receptor for the Parvovirus Capsid and Effects of Altered Affinity on Cell Uptake and Infection

Canine parvovirus (CPV) and its relative feline panleukopenia virus (FPV) bind the transferrin receptor type 1 (TfR) to infect their host cells but show differences in the interactions with the feline and canine TfRs that determine viral host range and tissue tropism. We changed apical and protease-...

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Detalhes bibliográficos
Main Authors: Goodman, Laura B., Lyi, Sangbom M., Johnson, Natalie C., Cifuente, Javier O., Hafenstein, Susan L., Parrish, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863798/
https://ncbi.nlm.nih.gov/pubmed/20200243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02623-09
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