Identification and Characterization of Clevudine-Resistant Mutants of Hepatitis B Virus Isolated from Chronic Hepatitis B Patients

Clevudine (CLV) is a nucleoside analog with potent antiviral activity against chronic hepatitis B virus (HBV) infection. Viral resistance to CLV in patients receiving CLV therapy has not been reported. The aim of this study was to characterize CLV-resistant HBV in patients with viral breakthrough (B...

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Autori principali: Kwon, So Young, Park, Yong Kwang, Ahn, Sung Hyun, Cho, Eun Sook, Choe, Won Hyeok, Lee, Chang Hong, Kim, Byung Kook, Ko, Soon Young, Choi, Hyo Sun, Park, Eun-Sook, Shin, Gu Choul, Kim, Kyun-Hwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863790/
https://ncbi.nlm.nih.gov/pubmed/20164224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02066-09
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