Adenovirus Protein E4orf4 Induces Premature APC(Cdc20) Activation in Saccharomyces cerevisiae by a Protein Phosphatase 2A-Dependent Mechanism

Protein phosphatase 2A (PP2A) has been implicated in cell cycle progression and mitosis; however, the complexity of PP2A regulation via multiple B subunits makes its functional characterization a significant challenge. The human adenovirus protein E4orf4 has been found to induce both high Cdk1 activ...

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Main Authors: Mui, Melissa Z., Roopchand, Diana E., Gentry, Matthew S., Hallberg, Richard L., Vogel, Jackie, Branton, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Transformation and Oncogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863776/
https://ncbi.nlm.nih.gov/pubmed/20164229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02434-09
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