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Role of Herpes Simplex Virus ICP0 in the Transactivation of Genes Introduced by Infection or Transfection: a Reappraisal

ICP0, a promiscuous transactivator that enhances the expression of genes introduced by infection or transfection, functions in both nucleus and cytoplasm. The nuclear functions include degradation and dispersal of ND10 bodies and suppression of silencing of viral DNA. Subsequently, ICP0 shifts to th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kalamvoki, Maria, Roizman, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863771/
https://ncbi.nlm.nih.gov/pubmed/20164233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02585-09
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