Mechanistic Consequences of hnRNP C Binding to Both RNA Termini of Poliovirus Negative-Strand RNA Intermediates

The poliovirus 3′ noncoding region (3′ NCR) is necessary for efficient virus replication. A poliovirus mutant, PVΔ3′NCR, with a deletion of the entire 3′ NCR, yielded a virus that was capable of synthesizing viral RNA, albeit with a replication defect caused by deficient positive-strand RNA synthesi...

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Bibliografiske detaljer
Main Authors:	Ertel, Kenneth J., Brunner, Jo Ellen, Semler, Bert L.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2010
Fag:	Genome Replication and Regulation of Viral Gene Expression
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2863767/ https://ncbi.nlm.nih.gov/pubmed/20164237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02198-09
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Mechanistic Consequences of hnRNP C Binding to Both RNA Termini of Poliovirus Negative-Strand RNA Intermediates

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