Expression of Type III Interferon (IFN) in the Vaginal Mucosa Is Mediated Primarily by Dendritic Cells and Displays Stronger Dependence on NF-κB than Type I IFNs

Interferons (IFNs) are induced as an initial response to viral infection after recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs). Here, we report that different PAMPs induce type I and III IFN expression at different ratios after mucosal administra...

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Bibliographic Details
Main Authors:	Iversen, Marie B., Ank, Nina, Melchjorsen, Jesper, Paludan, Søren R.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2010
Subjects:	Pathogenesis and Immunity
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2863761/ https://ncbi.nlm.nih.gov/pubmed/20181703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02591-09
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Expression of Type III Interferon (IFN) in the Vaginal Mucosa Is Mediated Primarily by Dendritic Cells and Displays Stronger Dependence on NF-κB than Type I IFNs

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