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Separable Functions of the Fission Yeast Spt5 Carboxyl-Terminal Domain (CTD) in Capping Enzyme Binding and Transcription Elongation Overlap with Those of the RNA Polymerase II CTD

An interaction network connecting mRNA capping enzymes, the RNA polymerase II (Pol II) carboxyl-terminal domain (CTD), elongation factor Spt5, and the Cdk7 and Cdk9 protein kinases is thought to comprise a transcription elongation checkpoint. A crux of this network is Spt5, which regulates early tra...

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Detalles Bibliográficos
Main Authors: Schneider, Susanne, Pei, Yi, Shuman, Stewart, Schwer, Beate
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863715/
https://ncbi.nlm.nih.gov/pubmed/20231361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00116-10
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