Cyclin-Dependent Kinase 8 Positively Cooperates with Mediator To Promote Thyroid Hormone Receptor-Dependent Transcriptional Activation

Mediator is a multisubunit assemblage of proteins originally identified in humans as a coactivator bound to thyroid hormone receptors (TRs) and essential for thyroid hormone (T3)-dependent transcription. Cyclin-dependent kinase 8 (CDK8), cyclin C, MED12, and MED13 form a variably associated Mediator...

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Autori principali: Belakavadi, Madesh, Fondell, Joseph D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863696/
https://ncbi.nlm.nih.gov/pubmed/20231357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01541-09
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