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Affinity of Ceftaroline and Other β-Lactams for Penicillin-Binding Proteins from Staphylococcus aureus and Streptococcus pneumoniae

We compared the affinities of ceftaroline for all penicillin-binding proteins (PBPs) with those of ceftriaxone and cefotaxime in 6 Staphylococcus aureus and 7 Streptococcus pneumoniae isolates with various resistance phenotypes. Ceftaroline MICs were ≤1 μg/ml against all S. aureus isolates and were...

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Bibliographische Detailangaben
Hauptverfasser: Kosowska-Shick, K., McGhee, P. L., Appelbaum, P. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863635/
https://ncbi.nlm.nih.gov/pubmed/20194704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00019-10
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