Single- and Multistep Resistance Selection Studies on the Activity of Retapamulin Compared to Other Agents against Staphylococcus aureus and Streptococcus pyogenes

Retapamulin had the lowest rate of spontaneous mutations by single-step passaging and the lowest parent and selected mutant MICs by multistep passaging among all drugs tested for all Staphylococcus aureus strains and three Streptococcus pyogenes strains which yielded resistant clones. Retapamulin ha...

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Bibliographic Details
Main Authors: Kosowska-Shick, Klaudia, Clark, Catherine, Credito, Kim, McGhee, Pamela, Dewasse, Bonifacio, Bogdanovich, Tatiana, Appelbaum, Peter C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366917/
https://ncbi.nlm.nih.gov/pubmed/16436741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.765-769.2006
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