Interaction of Candida albicans Biofilms with Antifungals: Transcriptional Response and Binding of Antifungals to Beta-Glucans

Candida albicans can form biofilms that exhibit elevated intrinsic resistance to various antifungal agents, in particular azoles and polyenes. The molecular mechanisms involved in the antifungal resistance of biofilms remain poorly understood. We have used transcript profiling to explore the early t...

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Bibliographic Details
Main Authors: Vediyappan, Govindsamy, Rossignol, Tristan, d'Enfert, Christophe
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863626/
https://ncbi.nlm.nih.gov/pubmed/20194705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01638-09
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