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Mechanism of Resistance of Hepatitis C Virus Replicons to Structurally Distinct Cyclophilin Inhibitors

The current standard of care for hepatitis C virus (HCV) infection, pegylated alpha interferon in combination with ribavirin, has a limited response rate and adverse side effects. Drugs targeting viral proteins are in clinical development, but they suffer from the development of high viral resistanc...

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Detalhes bibliográficos
Main Authors: Puyang, Xiaoling, Poulin, Danielle L., Mathy, Joanna E., Anderson, Leah J., Ma, Sue, Fang, Zheng, Zhu, Shejin, Lin, Kai, Fujimoto, Roger, Compton, Teresa, Wiedmann, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863619/
https://ncbi.nlm.nih.gov/pubmed/20176894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01236-09
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